What is this medication for?
Bevacizumab belongs to a group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as biological response modifiers. It is used in combination with certain types of chemotherapy medications to treat colon or rectal cancer and lung cancer that has spread to other parts of the body. While chemotherapy directly attacks a tumor, this medication works by stopping the tumor from forming new blood vessels.
Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are taking this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
What form(s) does this medication come in?
Avastin® is available as:
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
How should I use this medication?
The recommended adult dose of bevacizumab differs depending on the type of cancer and the other treatments being used. The usual dose ranges from 5 mg to 15 mg per kilogram of body weight given every 14 to 21 days as an intravenous infusion by your doctor.
The first dose should be given slowly over 90 minutes following chemotherapy, and if the side effects are acceptable, the second dose can be given over 60 minutes, before or after chemotherapy. If the side effects are still acceptable, future infusions can be given over 30 minutes.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Who should NOT take this medication?
Bevacizumab should not be used by anyone who is allergic to bevacizumab or to any of the ingredients of the medication.